I'm not saying don't raise your compression, but don't expect a 100+ HP gain, by just raising the compression from 12.5-14.5, with no other changes. HP don't come that easy.
My engine program shows a 16 HP gain on a methanol 582" engine making 970 HP, by raising the compression from 12.5/1, to 14.5/1, and it assumes the dome size needed to raise the compression, didn't start hindering flame travel, or causing some other combustion issues.
I think 16HP is more realistic, than 100+.
Randy