I can agre with previous poster except the same possibly applies to belts too. Gears do trasmit crank harmonics more into the cam.
I have built literally hundreds of engines over my lifetime. I have no idea how many and have never had a Cloyes True Roller Double Roller chain to break. I have engines in all horsepower ranges using the best Cloyes. Low to medium spring pressure engine I like the Hex-A-Just. It is much easier and is quicker to degree in. IN the high horsepowered and big strong spring pressure engine I like to use only the Cloyes Quik-Adjust which uses 6 perimter bolts in the two piece Billet Cam Gear. I have those on engines over 2,000 hp and with 460 # seat and over 1,250 lbs open pressures. No issues.
Do use Gear drives with engines using Roots styloe blowers with blower drives on front.
If it is a spring pressure lower than 225# seat I suggest the Cloyes Hex-Adjust. iF it is higer I suggest the Cloyes Quick-Adjust for more money. It is really nice.
Ed